What happens when biology meets Python programming?
In this project from Biology Course Batch 1 at Source Code Academia, students will explore the revolutionary science of CRISPR-Cas9 gene editing and learn how to build a Python-based tool for designing guide RNA.
Students will understand how CRISPR uses guide RNA as a biological GPS and Cas9 as molecular scissors to target specific DNA sequences. They will then apply computational biology to automate guide RNA design, identify candidate guide RNAs and off-target sites, evaluate quality, improve accuracy, and reduce human error.
This project is designed to prepare students for the rapidly growing fields of bioinformatics, genetics, biotechnology, computational biology, and medical research.
Help your child move beyond memorizing biology—and start building the future of science.
Chapters
00:00 How 20,000+ Genes Shape Human Life
00:15 How Genes Are Connected to Diseases
00:37 Bacteria’s Natural Defense Against Viruses
00:59 Guide RNA: The GPS of CRISPR
01:10 Cas9: The Molecular Scissors
01:41 How Scientists Target Specific DNA
02:05 DNA Repair and Gene Inactivation
02:23 Can a Diseased Gene Be Replaced?
02:51 Why Guide RNA Design Is Critical
03:18 Python-Based CRISPR-Cas9 Project
03:30 Building an Automated Guide RNA Tool
03:50 Candidate RNAs, Off-Targets and Quality Analysis
04:00 Improving Accuracy and Reducing Human Error
04:41 Preparing Future Computational Biologists
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